GRAPHENE-COATED OPTICAL FIBER SPR BIOSENSOR FOR BRCA1 AND BRCA2 BREAST CANCER BIOMARKER DETECTION: A NUMERICAL DESIGN-BASED ANALYSIS

Graphene-Coated Optical Fiber SPR Biosensor for BRCA1 and BRCA2 Breast Cancer Biomarker Detection: a Numerical Design-Based Analysis

Abstract This paper provides a simple hybrid design and numerical analysis of the graphene-coated fiber-optic surface plasmon resonance (SPR) biosensor for breast cancer gene-1 early onset (BRCA1) and breast cancer gene-2 early onset (BRCA2) genetic breast cancer detection.Two specific mutations named 916delTT and 6174delT in the BRCA1 and BRCA2 ar

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The EBNA3 family of Epstein-Barr virus nuclear proteins associates with the USP46/USP12 deubiquitination complexes to regulate lymphoblastoid cell line growth.

The Epstein-Barr virus (EBV) nuclear proteins EBNA3A, EBNA3B, and EBNA3C interact with the cell DNA binding protein RBPJ and regulate cell and viral genes.Repression of the CDKN2A tumor suppressor gene products p16(INK4A) and p14(ARF) by EBNA3A and EBNA3C is critical for EBV mediated transformation of resting B lymphocytes into immortalized lymphob

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App-based intervention for parents of children with crying, sleeping, and feeding problems: Usability, usefulness and implications for improvement

Background: There is a lack of evidence-based app guidance for parents of children with crying, sleeping, and feeding problems who are often highly burdened and not likely to seek professional help.A new psychoeducational app for parents providing scientifically sound information via text and videos, a diary function, selfcare strategies, a chat fo

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